someone even stopped a single of energy and i'm a consultant and strict medicine at
imperial college okay and it just stressed
so this paper a the purpose was to provide an updating to the benefits of
stem cell therapy instruments and
in terms of pre clinical evidence is very good evidence for benefits of stem cells
in straight models but in terms of translating that to the bedside that's very much
in its infancy stroke is a major calls mortality and morbidity across the world we
know that it is the seconds commonest single coils of that
worldwide and also be common discourse about of disability across the globe
so there's a real and pressing need to new treatments in the field of straight
medicine and perhaps regenerative strategy so just stem cell therapy and number of different theories
of been proposed which we discussed in the pay
this review article of written with my colleagues who have also worked on with the
clinical trial that were involved in and that is deborah williams and german chance when
s and i b
the commonest trees and this house themselves work is that you but a stem cell
into the damaged area and then a tree grows that a lot of that to
converge several conditions in terms of the brain and stroke
and there's very little evidence that that's house themselves what that they go in region
right resentment evidence for top lots of different types of stem cells
given to a stress induced straight models so animals at different times after straight and
given to animals by different methods of delivery for example direct implementation interest ripple implantation
given
systematically such as intravenously control theory some of these different things have been shown to
work in different trials
the challenge now is translating that's
to clinical arena and deciding which is the best type system so you when should
be can be giving it to locations of just wrote
how should be given to patients amongst a number of all this controls which we
discuss in the by already there are a number phase one phase two trolls which
have been completed or gabbing same in this paper we review and one of the
completed trials which been published and also give a summary of the ongoing trials
so
that is definitely a moving the right direction
but arts has been mentioned in the paper there are lots of challenges lots of
unanswered questions which need to be looked at in more detail and if we're going
to take this for which the key to success will be more coordinated research and
paying attention to expert opinion
from people that in this field as has been published in for example steps recommendations
which we mention in a paper