| 0:00:00 | hi i'm which one |
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| 0:00:01 | in doctor james dean felt and without a breakthrough worth your each answer magnetic then |
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| 0:00:07 | of particles |
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| 0:00:09 | the concept behind this is simple if you put iron particles in an alternating magnetic |
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| 0:00:13 | field they flip back and forth in create a lot of heat if they were |
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| 0:00:18 | inside a tumour you would could the cancer |
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| 0:00:20 | researchers have been trying to make this work for yes by the problem is i |
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| 0:00:25 | and it starts at their net |
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| 0:00:27 | you can avoid voicing the body i to correctly injecting into the tumour however |
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| 0:00:33 | this missus many areas and the tumour we grows we thought a better way |
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| 0:00:37 | would be to use intravenous |
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| 0:00:39 | or i the injection simply inject into a vein and that the circulatory system to |
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| 0:00:44 | a more even than the average of the cancer |
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| 0:00:47 | whatever is found to do this we first had make a random particles very nontoxic |
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| 0:00:52 | here in our problems we engineered an of particle with the night before and wrapped |
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| 0:00:57 | it in a pile compatible shell the i four will still react to it magnetic |
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| 0:01:02 | field but it's cap safely out of direct contact with the body |
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| 0:01:06 | the next problem was targeting on mac net and then of particles have to be |
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| 0:01:10 | the brass j |
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| 0:01:11 | and specifically target that formant we decided to take advantage of a natural property of |
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| 0:01:17 | cancer called e p r |
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| 0:01:19 | since to most of growing they call on the body to create not of new |
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| 0:01:23 | proposals in and around |
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| 0:01:25 | new blood vessels are leaky so anything of a particular size in the bloodstream will |
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| 0:01:30 | pass through and accumulate in the tumour but stay out of helping areas |
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| 0:01:34 | once we got a banana particle is to adjust the right size worked in a |
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| 0:01:39 | nap animal this after id ingestion |
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| 0:01:41 | that can was became high denoted with sixteen times the concentration in a global compared |
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| 0:01:46 | to the adjacent healthy tissues |
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| 0:01:48 | the next step was to put our test animals insider rapidly alternating magnetic field |
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| 0:01:53 | using an infrared camera to measure temperature we can see a working |
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| 0:01:58 | the tumours easily heat up to a lethal temperature they actually liquefied while surrounding healthy |
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| 0:02:03 | tissue stays cool and unharmed |
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| 0:02:06 | the results are dramatic with a single three minute treatment |
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| 0:02:09 | but to most are completely eradicated but the precision finer than the surgeon's knife we |
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| 0:02:15 | have achieved an actual curate of summary h and ninety percent in mice |
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| 0:02:19 | it's also great news for combinations there were cheating is used to greatly amplified human |
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| 0:02:24 | radiation so far it's been difficult to he deep tumours but magnetic seating is perfect |
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| 0:02:30 | for this |
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| 0:02:31 | the next step is really exciting or working with the national institutes of health |
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| 0:02:35 | and preparation for f d a probably need to bring dissipation |
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| 0:02:39 | as soon as possible |
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| 0:02:40 | there's a long road of testing ahead |
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| 0:02:43 | or where very hopeful |
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| 0:02:45 | with these very promising results |
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| 0:02:47 | to normal are please visit us and then a props outcome |
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