0:00:01are my dataset record and i work alongside and that i as a specialist s
0:00:06and standard and task and clinical research found between the department of physics and by
0:00:12the man i think be recorded
0:00:15my specialist interests in this topic detection and treatment of a base station blasting the
0:00:22nation's so while standard
0:00:25my research is based on american translation of noble by context techniques such as presents
0:00:32lifetime in the u s which ones
0:00:34in proc
0:00:39of these e is to provide a practical in the signal overview state-of-the-art imaging technology
0:00:47available simply use by the way
0:00:50that consonants and plastic nations
0:00:53of the gas and decided so
0:00:55i couldn't we detected and corrected eyes
0:00:58a task
0:01:00we didn't braces
0:01:01evaluation of all available modalities
0:01:04those in that they use as the last lose on the expert and identification of
0:01:11directions for future investigation
0:01:14the basic instrumentation and the basics behind each method
0:01:19followed by the most influential clinical experience on the slot
0:01:25particular emphasis is given to could be available techniques that still
0:01:30this interface and the consolidation such a small fluorescence imaging and confocal laser and the
0:01:37my cross
0:01:38rather than to do was already widely implemented in the planning prior
0:01:44what role in be saved
0:01:46for some of these techniques is the right guy the potential areas of money
0:01:51reducing uncertainties for both in both east and patient
0:01:56and reducing the time course and number of diagnostic purposes they
0:02:02in this respect the combination of coding techniques
0:02:06as well as integration of future potential optical imaging but not feast
0:02:11such as fluorescent python imaging across
0:02:15e anticipate
0:02:17this information might help guide future studies
0:02:21in this to and i the development of more actively a low cost and fast
0:02:27instrumentation
0:02:29i don't multiple we use a been previously described
0:02:33on this subject
0:02:35mostly due to the upper or lower yes and that's fine
0:02:39was this review tricycle both
0:02:43and you like to say to the signal into the approach
0:02:46to explore how each technique works
0:02:50i feel that this review represents
0:02:53i useful saws about the source
0:02:57contribution to the existing knowledge
0:03:02the next year slide i'll leave you want using the various clearly convenience
0:03:07and it could include all the buttons imaging modalities that are described in our read
0:03:14synthesize occurrences
0:03:16account for water all why consummate sob and they incidences right
0:03:22they provide the most
0:03:25compelling
0:03:26and
0:03:28indication for all stops
0:03:31these are the main still a clinical needs and us to decide and lost
0:03:37as you can see this major sources
0:03:40every station plastic lesions
0:03:42including a gas accounts for loops
0:03:45and that and that of a distinction in impulsive about disease
0:03:53false i over there are still not been found associated with two forty percent of
0:03:58high degree displays after the subject
0:04:03the current style the method for detecting distillation innovations we also
0:04:08is rather than four button by up to sprawled
0:04:11but this budget can easily be miss as only a small fraction of the bar
0:04:16to say
0:04:17it's
0:04:19also
0:04:20well i lost we cannot distinguish the steinem interpolation from this place you what of
0:04:25consonant duration not restore malignant
0:04:31the endoscopic appearance of
0:04:33only state such as a gas seconds
0:04:39consists of
0:04:40mean changes such as finally we also related i think so this derivation
0:04:45which can be easily overlooked
0:04:48and apart from japan only ten percent or yes they can serve as a detective
0:04:53at this stage in most of
0:04:58miss rates up to twenty five percent to call and ask you have been reported
0:05:03as well as this interval consists despite right that's a very
0:05:08in addition
0:05:10apparently falls i which have been proposed as one of the list
0:05:15stages of malignant transformation
0:05:17and platform which are characterized by a high malignant potential
0:05:22compare two sets often particularly important to sell to
0:05:27but the baseline we the standard wifi and lost
0:05:31this lady a malignant transformation
0:05:34we present the most important complication in patients and i met
0:05:39one of the major
0:05:40challenges and problems faced by clinicians e c is the logical finding of this place
0:05:47in random know how well as
0:05:50well be used in when you go to as the last microscopically normal and not
0:05:57in those time to visible beach
0:06:01in recent years a range of a novel techniques have been developed and clinical and
0:06:08but we aim of the dressing we use a mac clinical me
0:06:12some of these methods announced and optimize in that it can just available while others
0:06:18offer the possibility of assessing tissue structure every time a microscopic
0:06:26applied at least you is organized according to a proposed practical goal classification
0:06:33based on that by the g t and meanwhile ratified two thousand and eight
0:06:38so to give the reader a clear message on which technique is best suited n
0:06:42x more was training and detection for characterization of both
0:06:50various optical approaches have been investigated for the potential to provide and indeed a free
0:06:56optical helps to a diagnosis of gas and design of guns
0:07:02among these
0:07:03dresses lifetimes the chastity is an attractive technique plain use
0:07:08as you can be developed into real time of john for endoscopic examinations
0:07:14we use of a principal work by a group
0:07:17using wide few flame f than fifty five millimetres excitation on such specimens a problem
0:07:24can say that the
0:07:26and confocal three and four hundred and twenty nine the mean this
0:07:30excitation on and just like specimens of colon cancer right show that the fluorescence lifetime
0:07:37of plastic dish was consistently longer
0:07:41then that from surrounding known to plastic
0:07:44we don't need to translate fluorescence lifetime technology from the bench to the bedside our
0:07:50group has developed and the set called a single point wrestles lifetime
0:07:56system generating excitation and three hundred and seventy five ninety percent for other than thirty
0:08:01five millimetres efficiently side main indulgence
0:08:07and further research is currently on or
0:08:11finally i would like to thank all the phoneme boundaries for supporting our and the
0:08:15stop research projects and i hope you would enjoy reading ability